The fool is sometimes the first or the last arcana of tarot cards set. It is in fact a card without number.
It can be the sign of a travel but it is usualy a sign of a new beginning in your life.
If you leave your partner, if you leave your city to begin a new life. The fool is not the card of the little change, it is the card of the big change. If it comes regularly it is a sign.
Someone will leave you. You are or you will be lonely. The fool sense is more about you and your friends or family... Than you and your work or material things so if you usualy take the fool, it means that you will loose someone, not by death, but he will leave you, at work, at home...